Heart Organoids Screen for SARS-CoV-2 Infection and Inhibiting Drugs
October 19, 2021 | Terry Sharrer
“We [University of Cambridge] outline a screening platform using human embryonic stem cell-derived cardiomyocytes, confirmed to express the protein machinery critical for SARS-CoV-2 infection, and a SARS-CoV-2 spike-pseudotyped virus system. The method has allowed us to identify benztropine and DX600 as novel inhibitors of SARS-CoV-2 infection in a clinically relevant stem cell-derived cardiomyocyte line.” MORE
Image Credit: Nature.com