Growing Pancreatic Organoids

November 23, 2021 | | Posted in Newsletter

MIT Pancreatic organoids
“The gel they [engineers at MIT] developed is based on polyethylene glycol (PEG), a polymer that is often [MORE]

Brain Organoids with Parkinson’s Disease

November 23, 2021 | | Posted in Newsletter

Lewy Body–like Inclusions in Human Midbrain Organoids
“We [scientists at the National University of Singapore] identified for the first time that [MORE]

Human Brain Organoids with Optic Vesicles.

November 2, 2021 | | Posted in Newsletter

Human brain organoids assemble optical vesicles
“Using induced pluripotent stem cell (iPSC)-derived human brain organoids, we [researchers at Heinrich-Heine University, Dūsseldorf] [MORE]

Heart Organoids Screen for SARS-CoV-2 Infection and Inhibiting Drugs

October 19, 2021 | | Posted in Newsletter

Human embryonic stem cells derived cardiomyocytes screen SAR-CoV-2
“We [University of Cambridge] outline a screening platform using human embryonic stem cell-derived [MORE]

Gene Editing for Cystic Fibrosis

September 21, 2021 | | Posted in Newsletter

Evaluating CRISPR-based prime editing for cancer modeling
“Prime editing is a recently reported genome editing tool using a nickase-cas9 fused to [MORE]

Mechanical Stimulation influences Organoid Growth

September 7, 2021 | | Posted in Newsletter

Mechanical plasticity of collagen in mammary gland organoids
In both organ and tumor growth, chemical and mechanical signaling interact.  In this [MORE]

Advances in Kidney Organoids

August 31, 2021 | | Posted in Newsletter

Patterned kidney organoids
“Current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the [MORE]

Self-Organizing Cardioids

July 27, 2021 | | Posted in Newsletter

“With the notable exception of the human heart, lineage-specific self-organizing organoids have been reported for all major organs. Here, we [MORE]

Organoid Model of Cervical Cancer

June 29, 2021 | | Posted in Newsletter

Patient-derived organoid model for cervical cancer
“Researchers from the group of Hans Clevers (Hubrecht Institute) developed the first patient-derived organoid model [MORE]

“Crying” Organoids

May 18, 2021 | | Posted in Newsletter

Lacrimal gland organoids
“The tearful cultures, reported in Cell Stem Cell on 16 March, are the first tear-gland ‘organoids’ — three-dimensional [MORE]

Regenerating Bone from Stem Cells

May 4, 2021 | | Posted in Newsletter

Regenerating bone from stem cells
“This study reports the in vitro differentiation of human bone marrow stromal cells into a functional [MORE]

Blood Organoids

April 27, 2021 | | Posted in Newsletter

Mapping blood cell production in bone marrow
Hematopoiesis, other than taking place in bone marrow tissue, is poorly understood.  In this [MORE]

Organoids in Infectious Disease Research

February 9, 2021 | | Posted in Newsletter

Organoid applications
In 2009, Hans Clevers in The Netherlands first reported a method for growing and expanding human adult stem cell-derived [MORE]

Genetic Screening of Organoids

January 19, 2021 | | Posted in Newsletter

CRISPR-LIGHT tool for genetic screening tool for organoids
CRIPSR-Lineage Tracing at Cellular resolution in Heterogeneous Tissue (CRISPR-LICHT) is the term researchers [MORE]