Gene Editing’s Newcomers
October 25, 2016 | Terry Sharrer
CRISPR-Cas9 gene editing has created enormous scientific interest and it may soon antiquate itself as researchers around the world discover new cutting enzymes that are smaller than Cas9—small enough for viral vector delivery—or ones that target RNA sequences instead of DNA. Another approach relies on a bacterial protein family—the Argonautes—which function in RNA silencing. Small RNAs guide the Argonaute proteins to cleaving a specific mRNA and inhibiting translation. Other bacteria may yield new DNA or RNA cutting enzymes. MORE
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