POSTS TAGGED AS gene editing

A More Accurate Cas9 for Gene Editing

May 17, 2022 | | Posted in Newsletter

Structural basis for mismatch surveillance by CRISPR–Cas9
“Here we [researchers at the University of Texas at Austin] used kinetics-guided cryo-electron microscopy [MORE]

How Long Does Gene Editing Last?

May 17, 2022 | | Posted in Newsletter

How long doe gene editing last?
“. . . Intellia [Cambridge, MA] is presenting additional data from the phase 1 trial [MORE]

Gene Editing of Endothelial Cells

March 22, 2022 | | Posted in Newsletter

Gene Editing of Endothelial Cells
“To target endothelium for robust genome editing, we developed poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) (PEG-b-PLGA) copolymer-based nanoparticle [MORE]

AI Prediction of Protein Structure

February 1, 2022 | | Posted in Newsletter

DeepMind’s AI can predict protein shapes
Last December, Science named artificial intelligence software that calculates the shape of proteins as “the [MORE]

“Toehold” Switches for RNA Expression

January 4, 2022 | | Posted in Newsletter

RNA-responsive elements for eukaryotic translational control
In this piece, researchers at the Wyss Institute “. . .  introduce eukaryotic toehold switches [MORE]

Another Gene Editing System

November 30, 2021 | | Posted in Newsletter

New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]


November 23, 2021 | | Posted in Newsletter

Engineered miniature CRISPR-Cas system
Stanford bioengineers report: “we create an efficient miniature Cas system (CasMINI) engineered from the type V-F Cas12f [MORE]

Engineered Cells Implanted to Reduce Inflammation

November 16, 2021 | | Posted in Newsletter

Implant scaffold with engineered cells release drug to treat inflammation
Building on their work with anti-inflammatory cartilage cells, researchers at Washington [MORE]

Another Win for CRISPR

October 26, 2021 | | Posted in Newsletter

CRISPR therapy for rare blood diseases
“Back in 2019 the first CRISPR human clinical trials kicked off in the United States. [MORE]

Gene Editing for Cystic Fibrosis

September 21, 2021 | | Posted in Newsletter

Evaluating CRISPR-based prime editing for cancer modeling
“Prime editing is a recently reported genome editing tool using a nickase-cas9 fused to [MORE]

First in vivo Use of CRISPR-Cas9 in a Human

September 21, 2021 | | Posted in Newsletter

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
“Transthyretin amyloidosis . . . is a life-threatening disease characterized by progressive accumulation [MORE]

Retron Recombineering

July 6, 2021 | | Posted in Newsletter

Gene-editing tool “sneaks” DNA into cells without cuts
“Researchers [Wyss Institute] have created a new gene editing tool called Retron Library [MORE]

CRISPR’s On-Off Switch

June 8, 2021 | | Posted in Newsletter

CRISPR Off On switch
MIT and University of California at San Francisco have developed a process that better controls CRISPR gene [MORE]

Light-Activated Liposome in Gene Delivery

January 26, 2021 | | Posted in Newsletter

Spherical liposomes are light activated for CRISPR gene therapy
Because liposomes are considered safer than viral vectors for gene delivery, researchers [MORE]