Proteomics in Personalized Medicine
September 13, 2016 | Terry Sharrer
The “inherent biological differences between individuals,”. . . “cannot all be explained genetically.” Calling the sum and interaction of genes and proteins for each patient a “black box,” Swiss scientists used a new type of mass spectrometry known as SWATH-MS (an acronym for sequential window acquisition of all theoretical fragment ion spectra) to profile 2,600 proteins. Then, combining the proteomic data with genome sequencing, they carried out metabolic studies aimed at showing individual variations, publishing their findings as “System Proteomics of Liver Mitochondria Function.” MORE
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