Gene Therapy in the Brain
November 14, 2023 | Terry Sharrer
“[University of Minnesota] researchers evaluated a new form of gene therapy invented at the University of Minnesota — the PS [proprietary system] gene-editing system — in mice with Hurler syndrome. This approach created very high, continuous levels of normal enzymes in the liver that can enter the brain via the circulatory system. Using high resolution resting-state functional MRI (rs-fMRI) — a safe, noninvasive and whole-brain activity imaging tool for diagnosis and post-treatment evaluation — investigators first identified neural networks that were disrupted. Next, they assessed the extent to which brain functions and connectivity were restored following the gene therapy.” MORE
Image Credit: Lab-Worldwide.com
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