Monash University Scientists – Bullen, Das and Tripathti

A research collaboration between Australian and American scientists has found two genes (using CRISPR-Cas9 to make a loss of function screen) that controls the self-renewal of mouse embryonic stem cells.  These genes, TAF5L and TAF6L (for transcription associated factor, subunits 5L and 6L) effect the expression of the proto-oncogene c-Myc (for cellular Myelocytomatosis gene of an avian virus with human homology). This is an important finding for both stem cell science and cancer research.    MORE

Image Credit:  Monash University