January 31, 2023 | | Posted in Newsletter

New CRISPR gene-editing system can “drag-and-drop” DNA in bulk
A new technique has been added to the CRISPR gene-editing toolbox. Known [MORE]

CRISPR in Gene Therapy; Safety Issues

January 3, 2023 | | Posted in Newsletter

Terry Horgan was part of a trial of an experimental gene-editing therapy for muscular dystrophy
“The treatment, which was designated CRD-TMH-001, [MORE]

Some Gene Editing Targets Risk Toxicity and Instability

November 1, 2022 | | Posted in Newsletter

Study says gene editing with CRISPR/Cas9 can lead to cell toxicity and genome instability
“Scientists at IRB Barcelona [Institute for Research [MORE]

Gene Editing to Lower Cholesterol

October 11, 2022 | | Posted in Newsletter

Edits to a cholesterol gene could stop the biggest killer on earth
“A volunteer in New Zealand has become the first [MORE]

SHERLOCK for RNA Editing

September 27, 2022 | | Posted in Newsletter

CRISPR-Cas13 editing could offer new avenues for treatment
Scientists at the Broad Institute, who were involved in the technology of CRISPR [MORE]

CRISPR Skin Grafts Instead of Insulin Injections

September 13, 2022 | | Posted in Newsletter

Engineered epidermal progenitor cells can correct diet-Induced obesity and diabetes
Researchers at the University of Chicago have used CRISPR gene editing [MORE]

Gene Editing Shows Long Term Efficacy forBeta Thalassemia and Sickle Cell Disease

August 23, 2022 | | Posted in Newsletter

Sickle Cell Anemia
“In a late-breaking abstract presented at the European Hematology Association (EHA) Congress, a group of researchers that includes [MORE]

Compacting Cas for Precise Gene Editing

August 16, 2022 | | Posted in Newsletter

MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme
“It was already known that Cas7-11 is a combination of five [MORE]

“SuperFi” Gene Editing

June 14, 2022 | | Posted in Newsletter

SuperFi-Cas9 makes gene editing safer
“A recent study . . . at The University of Texas at Austin (TX, USA) reveals [MORE]

A More Accurate Cas9 for Gene Editing

May 17, 2022 | | Posted in Newsletter

Structural basis for mismatch surveillance by CRISPR–Cas9
“Here we [researchers at the University of Texas at Austin] used kinetics-guided cryo-electron microscopy [MORE]

AI Prediction of Protein Structure

February 1, 2022 | | Posted in Newsletter

DeepMind’s AI can predict protein shapes
Last December, Science named artificial intelligence software that calculates the shape of proteins as “the [MORE]


November 23, 2021 | | Posted in Newsletter

Engineered miniature CRISPR-Cas system
Stanford bioengineers report: “we create an efficient miniature Cas system (CasMINI) engineered from the type V-F Cas12f [MORE]

Gene Editing for Cystic Fibrosis

September 21, 2021 | | Posted in Newsletter

Evaluating CRISPR-based prime editing for cancer modeling
“Prime editing is a recently reported genome editing tool using a nickase-cas9 fused to [MORE]

First in vivo Use of CRISPR-Cas9 in a Human

September 21, 2021 | | Posted in Newsletter

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
“Transthyretin amyloidosis . . . is a life-threatening disease characterized by progressive accumulation [MORE]