CRISPR-Based Test for Cardiomyopathy

January 29, 2019 | | Posted in Newsletter

Hypertrophic cardiomyopathy
Most attention to CRISPR-Cas 9 has focused on editing out disease related genes, but this report tells of University [MORE]

The Scientist’s Top 10 Innovations of 2018

January 15, 2019 | | Posted in Newsletter

Fluidity One fluidic analytics
Here are ten notable technologies from “Cyto-Mine” that automatically performs all the steps in antibody discovery, to [MORE]


January 8, 2019 | | Posted in Newsletter

CRISPR-Cas9 Editing of the Genome
CRISPR-Cas9, as its name indicates, is a two-part technology.  CRISPR locates a target sequence, and Cas [MORE]

Prospects for CRISPR in the Clinic

October 30, 2018 | | Posted in Newsletter

Ex vivo CRISPR infographic
It is now more than a quarter century since the first authorized gene therapy clinical trial took [MORE]

T-Cell Engineering via Non-Viral Gene Editing

October 30, 2018 | | Posted in Newsletter

Genetically reprogrammed human T cells
Viral vectors have been the workhorses of gene transfer since the 1980s, but they always have [MORE]

CRISPR Versatility

June 26, 2018 | | Posted in Newsletter

HHMI Investigator Jennifer Doudna and Colleagues Created DETECTR
CRISPR is best known as a gene editing technology, but this report adds [MORE]

Metabolic Engineering

January 9, 2018 | | Posted in Newsletter

Huimin Zhao Developed Efficient Metabolic Engineering Process
CRISPR gene editing usually targets one DNA sequence at a time, but now researchers [MORE]

A Genetically Modified Skin Patch that Monitors Glucose Levels

December 12, 2017 | | Posted in Newsletter

Skin Patch that Monitors Glucose
In laboratory mice, University of Chicago bioengineers were able to use CRISPR gene editing to modify [MORE]

“Chemical Surgery” to Remove Single Point Mutations in DNA

November 14, 2017 | | Posted in Newsletter

Base Editing
CRISPR-Cas9 gene editing is the new tool in the box of molecular surgeons, but this method deletes multiple bases [MORE]

SHERLOCK for RNA Editing

September 26, 2017 | | Posted in Newsletter

Gene Editing
Scientists at the Broad Institute, who were involved in the technology of CRISPR gene editing, have developed another molecular [MORE]

CRISPR Skin Grafts Instead of Insulin Injections

September 12, 2017 | | Posted in Newsletter

Gene Therapy Via Skin
Researchers at the University of Chicago have used CRISPR gene editing to establish proof of concept in [MORE]

Targeting RNA with CRISPR

June 28, 2016 | | Posted in Newsletter

Feng Zhang
In a recent Science article, gene-editing pioneer Feng Zhang and colleagues reported a new CRISPR strategy that targets mRNA [MORE]

Cleveland Clinic’s Top Ten Innovations of the Year

December 8, 2015 | | Posted in Newsletter

Cleveland Clinic’s Innovation Summit highlights medical advances every year, and for 2015, out of 246 candidates, judges chose ten winners, [MORE]

CRISPR-Enabled Xenotransplants

December 8, 2015 | | Posted in Newsletter

Crystal Structure of Cas9
A pig’s heart is about the same size as a human’s, but a xenotransplant has not been [MORE]