POSTS TAGGED AS CRISPR

Engineering CRISPR against RNA Viruses

Treatment with Cas13d-NCS prevents the spread of SARS-CoV-2 (green)
“Here, we [at Helmholtz, Munich] show that the nuclear localization of Cas13d [MORE]

Clinical Success for Gene Editing, but at a Price None Could Afford

The first gene-editing treatment for Sickle Cell
“Many CRISPR treatments are in trials, but in 2022, Vertex Pharmaceuticals, based in Boston, [MORE]

Extracellular Vesicles for CRISPR Delivery

A conceptual depiction of the GEMINI technology for assembling custom gene delivery vehicles
“The first study to successfully use extracellular vesicles [MORE]

CRISPR-Based RNA Edit

CRISPR-Based editing of RNA viruses developed
“A new method of genome manipulation can rapidly engineer RNA viruses through precise cleavage and [MORE]

Bacteria as a Cancer Biosensor

Engineered Bacteria Detect Tumor DNA
“A new kind of biosensor has been created by an international team of researchers; they made [MORE]

Adenine Base Editing for Sickle Cell Disease

Base Editing Beats Other Genome Editing Strategies for Treating Sickle Cell Disease
“Base editing—the genome editing technique that alters base pairs [MORE]

AI Guidance for Gene Editing

AI and CRISPR Precisely Control Gene Expression
“Artificial intelligence (AI) can predict on- and off-target activity of CRISPR tools that target [MORE]

CRISPR Edited Organoids for Studying Fatty Liver Disease

NAFLD organoids offer insights and identify a potential therapeutic gene target
“Despite being an earlier disease stage, there’s relatively little focus [MORE]

A Senescent Cell Brain Tumor Vaccine

A vaccine could both  kill and prevent brain cancer using an unusual approach
“Researchers at Brigham and Women’s Hospital (MA, USA) [MORE]

Base-Editing Gene Therapy Cures a Child’s Incurable Leukemia

Teenager’s “incurable” leukemia cured by new base editing gene therapy
“A teenager in the UK has become the first person to [MORE]

CRISPR “PASTE”

New CRISPR gene-editing system can “drag-and-drop” DNA in bulk
A new technique has been added to the CRISPR gene-editing toolbox. Known [MORE]

CRISPR in Gene Therapy; Safety Issues

Terry Horgan was part of a trial of an experimental gene-editing therapy for muscular dystrophy
“The treatment, which was designated CRD-TMH-001, [MORE]

Some Gene Editing Targets Risk Toxicity and Instability

Study says gene editing with CRISPR/Cas9 can lead to cell toxicity and genome instability
“Scientists at IRB Barcelona [Institute for Research [MORE]

Gene Editing to Lower Cholesterol

Edits to a cholesterol gene could stop the biggest killer on earth
“A volunteer in New Zealand has become the first [MORE]