RNA Microsponges as Transporters
May 15, 2012 | Terry Sharrer
Chemical engineers at MIT have developed a new means for delivering therapeutics to targeted cells, calling their creation “RNAi microsponges (the “i” meaning “interfering”). The means of nanomanufacture is a polymerization process known as “rolling circle transcription.” When the microsponge adheres to a cell and delivers its “ball” of RNA’s; enzymes clip the sponge into about a half million gene-silencing particles that aim to block, say, a cancer pathway. MORE