An RNA switch for modulating gene expression
“The RNA-based switch controls mammalian gene expression through modulation of a synthetic polyA signal [MORE]
miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism
“Our [researchers at the University of California Davis] data [MORE]
AI and CRISPR Precisely Control Gene Expression
“Artificial intelligence (AI) can predict on- and off-target activity of CRISPR tools that target [MORE]
Cardiac muscle cells derived from cardiac fibroblasts. Fibroblast marker Fsp1 (red), cardiac muscle cell marker troponin I (green) and nuclei [MORE]
Computational tool ESPRESSO discovers and quantifies RNA isoforms
“Long-read RNA sequencing platforms could reveal variations in the transcriptome of rare genetic [MORE]
A Protein-Coding Portion of Telomeres is Discovered
“The repetitive sequences that compose telomeres were not thought to code for any proteins, [MORE]
Computational tool ESPRESSO discovers and quantifies RNA isoforms
“We [at Children’s Hospital of Philadelphia] present ESPRESSO, a computational tool for robust [MORE]
APLF and long non-coding RNA NIHCOLE promote stable DNA synapsis in non-homologous end joining
“Here, we [the National Biotechnology Center of [MORE]
CellREADR – Programmable RNA sensing for cell monitoring and manipulation
“Here we [neurobiologists, Duke University] describe CellREADR (Cell access through RNA [MORE]
CRISPR-Cas13 editing could offer new avenues for treatment
Scientists at the Broad Institute, who were involved in the technology of CRISPR [MORE]
Genome Editing with IscB-ωRNA
“In new research, Cornell scientists provide an explanation for how this problem [i.e. the large size of [MORE]
Pytheas- a software package for the automated analysis of RNA sequences
“To provide an analytical tool for sequence characterization of modified [MORE]
RNA-responsive elements for eukaryotic translational control
In this piece, researchers at the Wyss Institute “. . . introduce eukaryotic toehold switches [MORE]
New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]