Leukemia Trial Brings New Hope from Gene Therapy
October 11, 2011 | Terry Sharrer
This piece reports a gene therapy success against chronic lymphocytic leukemia for three patients at the University of Pennsylvania Cancer Center. The technique involved a recombinant viral vector engineered to express two antigens receptors found in CD19 positive malignancies (which is a subset of all CLL cancers). The virus transformed the patients own expanded T-cells against this cancer. Investigators in this trial also believe that their approach would work in non-Hodgkin lymphoma and acute lymphocytic leukemia. MORE