POSTS TAGGED AS viral vectors

Anellovirus Vectors in Gene Therapy

Ring’s ‘new class of viral vector’ is re-dosable in primates, overcoming key challenge of AAVs
“AAVs are the most commonly used [MORE]

Bigger Cargo Carriers for Gene Therapy

Gene therapy delivered via  a high-capacity baculovirus
“Here we [University of Bristol, UK] exploit the unmatched heterologous DNA cargo capacity of [MORE]

Brief History of Humanized Mice

Creating Genetically Humanized Mice
“Historically, genetic humanization of model organisms was achieved through one of two methods: random insertion transgenic humanization [MORE]

Gene Transfer with an Optic Adeno-Associated Viral Vector

Design and mode of function of the light-controlled viral transduction system
German and Chinese bioengineers have used “an adeno-associated viral (AAV) [MORE]

Sonothermogenetics

Deep Brain Stimulation Using Ultrasound and Genetic Modification
“Researchers at Washington University in St. Louis have developed a technique they call [MORE]

Safer Viral Vectors

George Church launches gene therapy startup to design safer viral vectors
A bioengineering team at Harvard “has developed a way to [MORE]

Reaching for the Next generation Gene Therapy

Advancing gene therapy
Two beguiling questions have vexed gene therapy from the beginning: how safe and effective are the vectors, and [MORE]

Trouble Shooting Gene Therapy

Gene therapy via viral vector
Making safe and serviceable viral vectors for gene therapy has many challenges—from empty to overfilled AAV [MORE]

AAV Production Accelerator for Gene Therapy

Adeno-associated virus serotype
Adeno-associated viral vectors are a workhorse for gene transfer protocols.  Getting enough AAV for gene therapy however has [MORE]

Gene Editing with CRISPR-Cas14

Gene editing
The founder of Mammoth Biosciences (South San Francisco, CA) explains in this piece the advantages of using the Cas-14 [MORE]

Editing Stem Cells in the Body

Editing stem cells in the body
In animal studies, Harvard bioengineers loaded CRISPR gene editing sequences into adeno-associated viruses, added red [MORE]

T-Cell Engineering via Non-Viral Gene Editing

Genetically reprogrammed human T cells
Viral vectors have been the workhorses of gene transfer since the 1980s, but they always have [MORE]

A Gene and Cell Therapy “Factory” in Houston

Gene Therapy
Following closely on the news that the world’s first commercial factory (30,000 sq. ft.) for the production of induced [MORE]

Non-Viral Vectors for CRISPR Delivery

MIT CRISPR Gene Editing Tool Without Viruses
CRISPR-Cas9 gene editing has mostly depended on viral vectors to deliver the cutting enzyme [MORE]