Biomaterial-Mediated Gene Therapy
April 22, 2014 | Terry Sharrer

Engineered Tissue
Since the beginning of gene therapy in 1990, clinical researchers have used genetically engineered viral vectors to deliver the therapeutic DNA. Taking that another step further, biomedical engineers at Duke University implanted viral vector particles on polymer scaffolds constructed to grow new tissue from stem cells. The vectors included transgenes for growth factors and the stem cells took up the viruses as they grew new cartilage. The biodegradable scaffolds eventually dissolved. MORE
Image Credit: Charles Gersbach and Farshid Guilak, Duke University and ScienceDaily. com