New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]
Engineered miniature CRISPR-Cas system
Stanford bioengineers report: “we create an efficient miniature Cas system (CasMINI) engineered from the type V-F Cas12f [MORE]
Implant scaffold with engineered cells release drug to treat inflammation
Building on their work with anti-inflammatory cartilage cells, researchers at Washington [MORE]
CRISPR therapy for rare blood diseases
“Back in 2019 the first CRISPR human clinical trials kicked off in the United States. [MORE]
Evaluating CRISPR-based prime editing for cancer modeling
“Prime editing is a recently reported genome editing tool using a nickase-cas9 fused to [MORE]
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
“Transthyretin amyloidosis . . . is a life-threatening disease characterized by progressive accumulation [MORE]
Gene-editing tool “sneaks” DNA into cells without cuts
“Researchers [Wyss Institute] have created a new gene editing tool called Retron Library [MORE]
CRISPR Off On switch
MIT and University of California at San Francisco have developed a process that better controls CRISPR gene [MORE]
Spherical liposomes are light activated for CRISPR gene therapy
Because liposomes are considered safer than viral vectors for gene delivery, researchers [MORE]
CRISPR-LIGHT tool for genetic screening tool for organoids
CRIPSR-Lineage Tracing at Cellular resolution in Heterogeneous Tissue (CRISPR-LICHT) is the term researchers [MORE]
Winners of 2020 Nobel Prize in Chemistry
Recombinant DNA and CRISPR gene editing are watershed technologies for the life sciences. But [MORE]
Improved CRISPR Cas9
Off targeting has always been a problem for the otherwise remarkable CRISPR-Cas9 gene editing technology. To improve the [MORE]
Crispr Cas9 molecular scissors
Computational biologists at the Institute for Basic Science (Daejeon, South Korea) have identified thirteen different variations of [MORE]
Base editing for restoring hearing in mice
From Harvard researchers: “[We] used base editing methods to treat a mouse model of [MORE]