Sensing High Metastatic Potential
February 12, 2019 | Terry Sharrer
Researchers at the UCSD medical school have identified a protein that has a high correlation with the potential of a cancer cell to metastasize. “The tyrosine-phosphorylated CCDC88A protein and its modified form were shown to occur only in solid tumor cells. Fluorescent signals associated with the alteration, observed with biosensors and by microscopy, could be an indicator of metastatic potential. Fluorescence resonance energy transfer (FRET) biosensors were designed by documenting this migration tendency and the likely evolution of single cancer cells.” MORE
Image Credit: UCSD