Nanotherapy prevents both arterial and venous thrombosis

“Researchers from University Hospitals Cleveland Medical Center and Case Western Reserve University (both OH, USA) have identified a targetable pathway to mitigate both arterial and venous thrombosis, two different types of blood clots. They used this to develop a novel nanotherapy, which has had promising preclinical results and could lead to safer ways to treat patients experiencing clotting, without increasing the risk of bleeding.  . . . .   A cluster of receptors that are unique to activated neutrophils was also identified, and the researchers used this to develop an antibody-coated nanoparticle that targets those clusters to stop this process and prevent blood clots. The researchers explained that for the first time, it’s been shown that arterial and venous thrombosis are driven by neutrophils and that targeting these white blood cells decreases clotting risk without increasing the risk of bleeding.”    MORE

Image Credit:  Biotechniques.com