Digital PCR in Identifying Copy Number Variations of Cancers
April 11, 2023 | Terry Sharrer
“Digital PCR outperforms many established methods for detecting CNAs. For example, in addition to having a short turnaround time, the high quantitative and qualitative accuracy of dPCR is superior to methods such as: qPCR, which requires standards and also provides low resolution, leaving it susceptible to false negatives; DNA microarrays, which are costly, require more input sample, and offer low resolution; FISH (fluorescent in situ hybridization), which is expensive, time-consuming, and low-throughput; and next-generation sequencing (NGS), which is costly, complex in terms of workflow and analysis, and prone to variable false-positive rates.” MORE
Image Credit: MDPI