The evolution of proteomics

In a series of interviews with leading proteomic researchers, five key challenges surfaced as barriers to making proteomics as dynamic as genomics.  The challenges are: 1) the need for high throughput analysis of biologically relevant single cells; 2) overcoming the technical demands of mass spectroscopy in sample processing, separation science, and modifications of peptides and proteins; 3) not having a “moon shot” project that captures broad attention; 4) making mass spectroscopy easier to use, with greater robustness; and 5) measuring low abundance proteins, such as transcription factors, that can be highly influential.   Simplifying these observations, researchers are clearly looking for advances in automation and informatics. MORE

Image Credit:   Technologynetworks.com