Huntington’s RNAs Inhibit Cancer Growth
May 29, 2018 | Terry Sharrer
Researchers at Northwestern University have discovered that the trinucleotide repeats (TNRs) associated with Huntington’s disease also are toxic to brain tumor cells. As this piece says: “The siRNAs found in Huntington’s kill cancer cells by targeting genes with complementary TNRs. Using the molecules [these scientists] were able to induce cell death in human and mouse ovarian, breast, prostate, liver, brain, lung, skin, and colon cancer cell lines. They also slowed tumor growth in mice with human ovarian cancer, with no toxicity to normal tissues.” That group next hopes to use nanoparticles to deliver TNR-based small interfering RNA’s. MORE
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