Exome Sequencing for Hypertension
March 6, 2012 | Terry Sharrer
With low-cost clinical genomic sequencing coming sooner than most medical experts expected, the question still is how useful will it really be? This piece raises one example: researchers at Yale recently sequenced several exomes (active genes) of people with high blood pressure, and found a new mechanism for hypertension, involving two mutations, one classically dominant or recessive and the other predominantly de novo. The ability to diagnose hypertension at birth or at any time before serious symptoms appear could have a great ameliorating effect on one of humankind’s biggest killers. MORE