Prospects for CRISPR in the Clinic
October 30, 2018 | Terry Sharrer
It is now more than a quarter century since the first authorized gene therapy clinical trial took place. Questions remain—is it safe?, what are the unintended consequences?, is it ethical? But such questions haven’t be insurmountable, as 2,579 clinical trials have proceeded in thirty-eight countries (for an overview, SEE. The most impressive successes have come using CRISPR gene editing in cancer immunotherapies (involving CAR-T cells for blood cancers). MORE
Image Credit: The Scientist