The first gene-editing treatment for Sickle Cell
“Many CRISPR treatments are in trials, but in 2022, Vertex Pharmaceuticals, based in Boston, [MORE]
One-off gene-editing treatment lowers inherited bad cholesterol levels
“In heterozygous familial hypercholesterolemia (HeFH), people inherit one gene that results in very [MORE]
Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses
“Here, we [at the McGovern Brain Institute, MIT] characterize Fanzors [MORE]
Pig Kidney Xenotransplantation Performing Optimally After 32 Days in Human Body
“Surgeons at NYU Langone Health have transplanted a genetically engineered [MORE]
A step toward stem cell engineering in Vivo
“Breda et al. [Children’s Hospital of Philadelphia] designed a strategy to reprogram bone [MORE]
Base Editing Beats Other Genome Editing Strategies for Treating Sickle Cell Disease
“Base editing—the genome editing technique that alters base pairs [MORE]
AI and CRISPR Precisely Control Gene Expression
“Artificial intelligence (AI) can predict on- and off-target activity of CRISPR tools that target [MORE]
Peptide Assisted Gene Editing (PAGE)
“In the study, researchers [at the University of Pennsylvania] explored the use of small, virus-derived protein [MORE]
Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs
“Here we [researchers at Kyushu University, Fukuoka, Japan] [MORE]
Changing the brain- nanocapsule therapy edits the Alzheimer’s gene
“Researchers at the University of Wisconsin–Madison (WI, USA) have developed a nanocapsule [MORE]
A vaccine could both kill and prevent brain cancer using an unusual approach
“Researchers at Brigham and Women’s Hospital (MA, USA) [MORE]
Teenager’s “incurable” leukemia cured by new base editing gene therapy
“A teenager in the UK has become the first person to [MORE]
New CRISPR gene-editing system can “drag-and-drop” DNA in bulk
A new technique has been added to the CRISPR gene-editing toolbox. Known [MORE]
CellREADR – Programmable RNA sensing for cell monitoring and manipulation
“Here we [neurobiologists, Duke University] describe CellREADR (Cell access through RNA [MORE]