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T-Cell Engineering via Non-Viral Gene Editing

Genetically reprogrammed human T cells
Viral vectors have been the workhorses of gene transfer since the 1980s, but they always have [MORE]

Growing Up Kidney Podocytes

Mature kidney podocyte
Winston Churchill’s comment that Russia is “a riddle wrapped in a mystery inside an enigma” might equally apply [MORE]

The First MRI-Guided Neurosurgical Robot

Robot prototype operating within MRI environment
Metal objects used in surgeries are incompatible with the magnetic field of MRI imaging. To work [MORE]

Computer Designed Regenerative Heart Valves

Computer-designed customized regenerative heart valve
For children born with defective heart valves, repair solutions are limited, mainly because a prosthesis has [MORE]

Gene Mapping for Targeted Chemotherapy

Breast Cancer Cell
Anti-cancer chemotherapy originally derived from chemical warfare studies in 1942. Alfred Gilman and Louis Goodman discovered the effect [MORE]

Skeletal Regeneration from Bone Marrow Stem Cells

Development of Cartilage Tissue from Stem Cells (red)
“Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely [MORE]

“Bridged Nucleic Acid” as a Guide for Gene Editing

B-DNA
A synthetic guide molecule appears to increase the targeting accuracy in CRISPR-Cas9 gene editing, according to a research group at [MORE]

Liver Regeneration

Telomerase
An adult’s liver can fully regenerate its original mass from as little as 25% of its remaining undamaged or diseased [MORE]

Bacterial Cellulose for Artificial Tissues?

Bacterial Cellulose Bio-fabrication as Ear
“BC [bacterial cellulose], one of the purest forms of nanocellulose, is produced at the interface between [MORE]

Injectable Hydrogel for Diabetic Ulcers

Rice University Graduate Student Nicole Carrejo Analyzes a Sample of K2(SL)6K2
Treating diabetic foot ulcers is an art left behind. Little [MORE]

Listening to “Silent Seizures”

Brain Stethoscope
Convulsions are dramatic symptoms of epilepsy, but seizures can also be silent and not obvious. To diagnose such silent [MORE]

4-D Printing

4D Printing Low Temperature
Temperature is the fourth dimension in this piece. Rutgers University engineers “used a lithography-based technique that’s fast, [MORE]

First in vitro Kidney Tissue

Kidney Glomeruli
In a first for regenerative medicine, bioengineers at the University of Manchester have grown functional human kidney tissue organelles [MORE]

Measuring Cell Strength Indicating Hypertension

Measuring the Strength of Macrophages
A new high-throughput device measures cell strength—important information for determining drug efficacy for hypertension, asthma, muscular [MORE]