Drug Delivery via Nanodisks
May 31, 2011 | Terry Sharrer
All mammalian cells contain naturally occurring nanoparticles called “vaults” that resemble, in their lipid bilayer structure, artificial liposomes used in gene therapy delivery. The difference is that vaults are nanoscale and liposomes are microscale. Manufactured vaults have potential for drug delivery, and researchers at UCLA not only have made artificial vaults, but also have engineered nanodisks, carrying drug cargos, that can go inside the vaults and slowly release a small molecule drug to a specific cellular target. MORE