Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus

“We [ophthalmology and materials researchers at Linkoping University in Sweden] describe a cell-free engineered corneal tissue, bioengineered porcine construct, double crosslinked (BPCDX) and a minimally invasive surgical method for its implantation. In a pilot feasibility study in India and Iran (clinicaltrials.gov no. NCT04653922), we implanted BPCDX in 20 advanced keratoconus subjects to reshape the native corneal stroma without removing existing tissue or using sutures. During 24 months of follow-up, no adverse event was observed.”  MORE

Image Credit:  Nature.com