“Regulator of Cartilage Growth and Differentiation”
April 10, 2018 | Terry Sharrer
Thinking there might be an injectable therapy instead of joint replacement in some cases of arthritis, researchers at the University of Southern California have discovered a molecule called “RCGD 423” that might be the answer. “It works by communicating with a molecule in the body, called the glycoprotein 130 (Gp130) receptor. The Gp130 is capable of receiving two types of signals from the body, namely those that promote cartilage development in the embryo, and those that trigger chronic inflammation in the adult. RCGD 423 boosts the Gp130’s ability to receive the cartilage development signals (which leads to cartilage regeneration, even in adults), and blocks the inflammatory signals.” MORE
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