Mass Producing Livers
Using a custom designed micro-well cell plate that has a film which nourishes liver stem cells, researchers at Cincinnati Children’s Center for Stem Cell and Organoid Medicine, and at Yokohama City University, have created means for mass producing liver organoids. As this piece says, “The new process allows researchers to bioengineer single batches of up to 20,000 genetically matched, three-dimensional and highly functional liver micro-buds. When combined, the batch has a sufficient quantity of liver cells and size feasibility for transplant into a person with liver failure, or for drug testing. The liver tissues were also generated entirely from human induced pluripotent stem cells (iPSCs), making the process free of animal feeder byproducts used to make cells for research purposes – a barrier to the cells being used therapeutically.” MORE
Image Credit: Cincinnati Children’s Center for Stem Cell and Organoid Medicine and Yokohama City University, MDTMag.com