Reverting Pluripotent Stem Cells to Totipotency
August 23, 2022 | Terry Sharrer
“In recent years scientists have been able to take adult cells and induce a pluripotent state in them, which forms the basis of research into stem cell regenerative medicine. But in the new study, the Tsinghua [University] team took things a step further, returning pluripotent stem cells to a totipotent state for the first time. The researchers started by screening thousands of combinations of small molecules, until they identified a particular mix of three that seemed to induce totipotency in pluripotent stem cells from mice. They named their concoction the TAW cocktail, after the three molecules in it – TTNPB, 1-Azakenpaullone, and WS6.” MORE
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