Theradaptive harnessing regeneration

With collaborators at MIT and Harvard, Luis Alvarez’s company Theradaptive “. . .  has developed a method to coat orthopedic implants with other molecules that might improve healing, such as a variation of bone morphogenetic protein 2 (BMP2), which is already used clinically to promote bone regeneration after spine surgery and other bone-related procedures. In work conducted with collaborators at Cleveland Clinic and presented at the 2020 Orthopedic Research Society Meeting, Alvarez and his colleagues found that goats treated for a 5-centimeter defect in a limb with a standard surgical procedure and an implant coated with Theradaptive’s BMP2 variant, called AMP2, exhibited complete healing in the bone, while those treated with the uncoated implant did not. The company hopes to begin clinical trials of AMP2 next year.”  MORE

Image Credit:  Theradaptive