It Depends on how You Grow Stem Cells
March 12, 2019 | Terry Sharrer
Stem cell biologists at Osaka University have found that by growing human iPSCs in the different extracellular matrix proteins known as “laminins,” that could selectively generate corneal and retinal cells. “Specifically, the 211 isoform of the E8 fragment of laminin (LN211E8) promotes differentiation into neural crest cells via Wnt activation, whereas LN332E8 promotes differentiation into corneal epithelial cells.” There are 15 laminin trimers, made up of alpha, beta and gamma chains. MORE
Image Credit: Osaka University and Cell.com