Photoinduced Cycloisomerization
September 11, 2018 | Terry Sharrer

Synthesizing carbocyclic 5-8-5 fused-ring-systems
Florida State University biochemists have used UV light to synthesize the carbocyclic ring that should be useful in forming nucleoside analogs for antiviral drugs. According to this piece: “. . . cyclization substrates — the underlying structures upon which the ring frameworks are built — can be accessed via a simple two-step assembly scheme. With a reliable substrate in place, the full 5-8-5 scaffold is accomplished in one, highly controlled operation with UV light employed to promote ring formation.” MORE
Image Credit: Florida State University News