Growing Cells on Mirrors for Advanced Microscopy
Research collaborators at Georgia Tech, Peking University and the University of Technology Sydney have developed a new way to view cells in microscopy on three axes. “The new technique, known as mirror-enhanced, axial narrowing, super-resolution (MEANS) microscopy, begins with growing cells to be studied on a tiny mirrors custom-made by a manufacturer in China. A glass cover slide is placed over the cells, and the mirror placed into a confocal or wide-field microscope in the place of a usual clear slide. The technique improves axial resolution six-fold and lateral resolution two-fold for Stimulated Emission Depletion (STED) nanoscopy. The ability to increase the resolution and decrease the thickness of an axial section without increasing laser power is of great importance for imaging biological specimens, which cannot tolerate high laser power. . . .” MORE
Image Credit: John Toon, Georgia Tech and MDTMag.com