ANGPTL4

In a DNA sequencing study that involved 54,000 SNPs, in 13,715 genes, among almost 73,000 patients with coronary artery disease (and 120,000 control subjects), German researchers at the Technical University of Munich, found that a point mutation in the ANGPTL4 (angiopoietin-like 4) gene, which results in lower triglyceride numbers, confers a 50% lower risk for heart attack. Among other things, this could indicate that drugs which specifically target the ANGPTL4 gene could reduce vascular disease.   MORE

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