Light-Scattering for Chemo Effectiveness
March 24, 2009 | Terry Sharrer
Angle-resolved low coherence interferometry (a/LCI) is a technology that allows oncologists to determine how effectively an anticancer drug is working. In conventional practice, the oncologist gives chemotherapeutics and then waits for weeks before using a MRI or PET image to tell if a tumor has decreased its mass. Researchers at Duke, however, published their work showing that light scattering can detect slight changes (fractal dimensions) in the nucleus or mitochondria indicating drug induced apoptosis-in 90 minutes. This might also show if tumor cells are resistant to certain drugs. MORE