POSTS TAGGED AS Genetic Engineering

Cell by Cell Changes in Xenotransplantation

Cellular dynamics in pig-to-human kidney xenotransplantation
“Early trials of porcine kidney xenotransplantation have been performed on brain-dead human recipients, but the [MORE]

Humanized COVID-19 Mouse

Mouse genome rewriting and tailoring of three important disease loci
“Here we [NYU Grossman School of Medicine] describe ‘mammalian switching antibiotic [MORE]

Smart Pill Colonoscopy

From left, team members Qijun Liu of Boston University, Maria Eugenia Inda of MIT, and Miguel Jimenez of MIT pose [MORE]

Engineered E. coli Advance Antitumor Immunity

Engineered bacteria deliver chemokines to alert the immune system to tumors
“Here, we [at Columbia University] engineer bacteria to intratumorally release [MORE]

Turning Gut Flora against Diabetes

Intestinal transgene delivery with native E. coli chassis allows persistent physiological change
“In this proof-of-concept study, we [gastroenterologists at the University [MORE]

History of Humanized Mice

History of Creating Genetically Humanized Mice
“Historically, genetic humanization of model organisms was achieved through one of two methods: random insertion [MORE]

Surgeons Use a Pig Kidney in a Human

Surgeons successfully  transplanted a pig kidney to a human
“The surgical team, from NYU Langone Health, attached the pig kidney to [MORE]

An Engineered Bacterium for Diagnosing a Human Disease

Engineered organism could diagnose Crohn’s disease flareups
“In an important step toward the clinical application of synthetic biology, Rice University researchers [MORE]

Retron Recombineering

Gene-editing tool “sneaks” DNA into cells without cuts
“Researchers [Wyss Institute] have created a new gene editing tool called Retron Library [MORE]

Semi-Synthetic Biology—“JCVI-syn3A”

Synthetic cell growing and dividing
From the J. Craig Venter Institute and collaborators at NIST and MIT comes this: “For the [MORE]

Lab-Made Mimic of SARS-CoV-2

Lab researcher
In order to engineer a virus that mimics SARS-CoV-2 without causing COVID-19’s severe symptoms, virologists at Washington University in [MORE]

Humanized Mouse Model for Study of Inherited Prion Disease

Creating transgenic mice that express prion disease
Until now, researchers studying animal models of prion diseases have had to introduce a [MORE]

Phage Therapy

Genetically engineered phage therapy
A teenage girl developed an antibiotic-resistant infection following a lung transplant to treat cystic fibrosis.  Her prospects [MORE]

Heat-Activated Immunotherapy

 
Heat-sensitive genetic switch for T cell
Georgia Tech bioengineers have developed means to control T-cells activity in cancer therapy.  They introduced a [MORE]