Improving Single Guide RNA Editing

July 11, 2023 | | Posted in Newsletter

Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs
“Here we [researchers at Kyushu University, Fukuoka, Japan] [MORE]

A More Accurate Cas9 for Gene Editing

May 17, 2022 | | Posted in Newsletter

Structural basis for mismatch surveillance by CRISPR–Cas9
“Here we [researchers at the University of Texas at Austin] used kinetics-guided cryo-electron microscopy [MORE]

Another Gene Editing System

November 30, 2021 | | Posted in Newsletter

New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]

A More Precise CRISPR

September 1, 2020 | | Posted in Newsletter

Improved CRISPR Cas9
Off targeting has always been a problem for the otherwise remarkable CRISPR-Cas9 gene editing technology.  To improve the [MORE]

“Prime Editing” with CRISPR

February 11, 2020 | | Posted in Newsletter

Prime editing system
MIT and Harvard researchers have developed a new means of CRISPR gene editing that they believe could correct [MORE]

CRISPR on a Chip

October 22, 2019 | | Posted in Newsletter

Digital DNA detection
First, affix a piece of graphene to a pyrene substrate.  Then, load Cas9 and guide RNA molecules onto [MORE]

How CRISPR Works

September 17, 2019 | | Posted in Newsletter

CRISPR-Cas9- how it works
This piece is a video TED talk featuring Jennifer Doudna talking about how she co-invented the CRISPR-Cas9 [MORE]


January 8, 2019 | | Posted in Newsletter

CRISPR-Cas9 Editing of the Genome
CRISPR-Cas9, as its name indicates, is a two-part technology.  CRISPR locates a target sequence, and Cas [MORE]

Human Immunity to Cas9 Proteins

February 6, 2018 | | Posted in Newsletter

CRISPR-Cas9 Gene Editing
Stanford researchers have reported troubling news about CRISPR-Cas9 gene editing. Their report “demonstrates that there are pre-existing humoral [MORE]