An RNA Switch for Modulating Gene Expression

March 5, 2024 | | Posted in Newsletter

An RNA switch for modulating gene expression
“The RNA-based switch controls mammalian gene expression through modulation of a synthetic polyA signal [MORE]

MicroRNA-22 Gene Therapy for Liver Cancer

October 31, 2023 | | Posted in Newsletter

miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism
“Our [researchers at the University of California Davis] data [MORE]

AI Guidance for Gene Editing

September 12, 2023 | | Posted in Newsletter

AI and CRISPR Precisely Control Gene Expression
“Artificial intelligence (AI) can predict on- and off-target activity of CRISPR tools that target [MORE]

Cellular Reprogramming Hearts after Infarction

July 18, 2023 | | Posted in Newsletter

Cardiac muscle cells derived from cardiac fibroblasts. Fibroblast marker Fsp1 (red), cardiac muscle cell marker troponin I (green) and nuclei [MORE]

Computational RNA tool, ESPRESSO

July 11, 2023 | | Posted in Newsletter

Computational tool ESPRESSO discovers and quantifies RNA isoforms
“Long-read RNA sequencing platforms could reveal variations in the transcriptome of rare genetic [MORE]

Protein Encoded in Telomere Genes

May 16, 2023 | | Posted in Newsletter

A Protein-Coding Portion of Telomeres is Discovered
“The repetitive sequences that compose telomeres were not thought to code for any proteins, [MORE]

RNA in My Espresso

May 16, 2023 | | Posted in Newsletter

Computational tool ESPRESSO discovers and quantifies RNA isoforms
“We [at Children’s Hospital of Philadelphia] present ESPRESSO, a computational tool for robust [MORE]

Magnetic Tweezers for Examining DNA Repair

May 2, 2023 | | Posted in Newsletter

APLF and long non-coding RNA NIHCOLE promote stable DNA synapsis in non-homologous end joining
“Here, we [the National Biotechnology Center of [MORE]

Reading Cellular RNA

December 20, 2022 | | Posted in Newsletter

CellREADR  – Programmable RNA sensing for cell monitoring and manipulation
“Here we [neurobiologists, Duke University] describe CellREADR (Cell access through RNA [MORE]

SHERLOCK for RNA Editing

September 27, 2022 | | Posted in Newsletter

CRISPR-Cas13 editing could offer new avenues for treatment
Scientists at the Broad Institute, who were involved in the technology of CRISPR [MORE]

Genome Editing with IscB-ωRNA

August 9, 2022 | | Posted in Newsletter

Genome Editing with IscB-ωRNA
“In new research, Cornell scientists provide an explanation for how this problem [i.e. the large size of [MORE]

Automated RNA Sequence Analysis

July 12, 2022 | | Posted in Newsletter

Pytheas- a software package for the automated analysis of RNA sequences
“To provide an analytical tool for sequence characterization of modified [MORE]

“Toehold” Switches for RNA Expression

January 4, 2022 | | Posted in Newsletter

RNA-responsive elements for eukaryotic translational control
In this piece, researchers at the Wyss Institute “. . .  introduce eukaryotic toehold switches [MORE]

Another Gene Editing System

November 30, 2021 | | Posted in Newsletter

New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]