Multigene Test for High Risk Heart Disease, et al

December 18, 2018 | | Posted in Newsletter

DNA Multigenic risk score
Polygenic risk scores may become as routine as cholesterol screening. To that end, researchers at the Broad [MORE]

Why Clinical Genetics Lags

December 18, 2018 | | Posted in Newsletter

Much of the Genome has not been studied
It’s true in most fields that new research largely reinforces prior discoveries.  That’s [MORE]

Predicting Adult Heart Attacks in Childhood

November 20, 2018 | | Posted in Newsletter

Most of what we know about cardiovascular disease “risk factors” comes from the longitudinal study of residents in Framingham, MA, [MORE]

Georgetown’s REMBRANT

October 9, 2018 | | Posted in Newsletter

REMBRANT is an acronym for Repository for Molecular Brain Neoplasms Data.  Originally, the National Cancer Institute compiled and organized the [MORE]

A Genome in a Day

September 4, 2018 | | Posted in Newsletter

In living cells, a special polymerase named “terminal deoxynucleotidyl transferase” (TdT) adds about a thousand nucleotides per second to a [MORE]

Best Known Genes

July 24, 2018 | | Posted in Newsletter

TP53 – one of the “popular” genes
Maybe medical research is another “Me Too” movement. In a survey of 40,000 Pub [MORE]

Geisinger on Routine Sequencing

July 17, 2018 | | Posted in Newsletter

Geisinger Health
“Precision medicine” based on DNA sequencing is all the buzz in healthcare except among payers who deem molecular profiling [MORE]

Growing Blood without A, B and RhD Antigens

July 17, 2018 | | Posted in Newsletter

Red blood cells
There are 36 different blood groups and more than 350 antigens on red blood cells that can cause [MORE]

Kaiser Permanente’s Research Biobank Is Currently Largest (Non-Governmental) in the US

December 19, 2017 | | Posted in Newsletter

Research Biorepository Kaiser Permanente
This piece should be read with an eye to the previous story about hacking DNA sequencers. The [MORE]

Perspective on DNA Sequencing

December 12, 2017 | | Posted in Newsletter

DNA 3D Model
Keep in mind that the Human Genome Project completed its “rough draft” only a dozen years ago; since [MORE]

A Cancer Pathology Gene Atlas

October 31, 2017 | | Posted in Newsletter

New Pathology Atlas Launched
Quoting directly: “A new Pathology Atlas has been launched with an analysis of all human genes in [MORE]

Metabolomics in Personalized Medicine

September 26, 2017 | | Posted in Newsletter

“You have tens of thousands of genes, of which tens of thousands will be expressed – and you also have [MORE]

Nanoparticle-Enabled Gene Editing

April 18, 2017 | | Posted in Newsletter

CRISPR Delivery Mechanism
Getting CRISPR-Cas 9 molecules to their target cells without damage or off-targeting has been an obstacle for gene [MORE]

Sequencing Every Species on Earth

April 11, 2017 | | Posted in Newsletter

Cell Types
Recently, researchers called together by the Smithsonian Initiative on Biodiversity Genomics, and the Beijing Genomics Institute, proposed launching a [MORE]