Saline + Albumin in Diluted Plasma Reverses Aging in Mice
August 11, 2020 | Terry Sharrer
From bioengineers at the University of California Berkeley: “using our recently developed small animal blood exchange process, we replaced half of the plasma in mice with saline containing 5% albumin (terming it a “neutral” age blood exchange, NBE) thus diluting the plasma factors and replenishing the albumin that would be diminished if only saline was used. Our data demonstrate that a single NBE suffices to meet or exceed the rejuvenative effects of enhancing muscle repair, reducing liver adiposity and fibrosis, and increasing hippocampal neurogenesis in old mice, all the key outcomes seen after blood heterochronicity.” MORE
Image Credit: Irina Conboy