Field Asymmetric Waveform Ion Mass Spectrometry (FAIMS)
July 28, 2020 | Terry Sharrer
“FAIMS is a differential ion mobility technique that spatially separates ionized species in the gaseous phase in the presence of strong and weak electric fields. Placed before the MS entrance, only ions with a specific mobility value and stable flight path exit into the MS to be detected and sequenced. To select which ion groups traverse the interface for MS analysis, a secondary direct current potential, the compensation voltage (CV), is applied to the inner electrode. Changing the CV selects different groups of ions and allows multiple unique precursors to be detected, giving increased coverage over FAIMS-free methods.” MORE
Image Credit: Thermo Fisher Scientific