“Swift” Method for 3D Printing of Organs
SWIFT cardiac tissue cross section
Once again, the bioengineers at the Wyss Institute live up to their motto of “biologically inspired engineering.” They report: “Organ building blocks (OBBs) composed of patient-specific–induced pluripotent stem cell–derived organoids offer a pathway to achieving tissues with the requisite cellular density, microarchitecture, and function. . . . Here, we report a biomanufacturing method for assembling hundreds of thousands of these OBBs into living matrices with high cellular density into which perfusable vascular channels are introduced via embedded three-dimensional bioprinting. The OBB matrices exhibit the desired self-healing, viscoplastic behavior required for sacrificial writing into functional tissue (SWIFT).” MORE
Image Credit: Wyss Institute
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