Monkeys cloned from a gene-edited macaque

This piece is thin on details, but it describes a new gene editing technique called “LEAPER” for leveraging endogenous ADAR for programmable editing of RNA.”  (An article in the July 15, 2019 issue of Nature Biotechnology, “Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs,” has the research report). A biologist at Peking University proposes that LEAPER is a safer way to do gene editing than CRISPR-Cas9, because only one molecule of RNA is used and it does not actually cut DNA.  Instead, it recruits enzymes, ADAR 1 and ADAR 2, which change a gene expression without making it heritable. MORE

Image Credit:  VCG and Global TImes