Gene Catalog of Cancer
January 1, 2019 | Terry Sharrer
How many genes can cause cancer? Researchers at the Wellcome Sanger Institute in England believe the number is more than 700. Quoting directly: “For the first time ever, functional changes to these genes are summarised in terms of the ten Cancer Hallmarks – biological processes that drive cancer. Mutations in some genes lead to errors in repairing DNA, whereas mutations in other genes can suppress the immune system or promote tumour invasion or spreading. Across the 700 genes in the Cancer Gene Census, many have two or more different ways of causing cancer. These are often different and sometimes contradictory depending on the tumour type and are all described in this single resource.” MORE
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