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POSTS TAGGED AS off targeting

Frameshifting with mRNA Therapeutics

February 13, 2024 | | Posted in Newsletter

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting
“Here we [MRC researchers at the University of Cambridge] demonstrate that incorporation of N1-methylpseudouridine [MORE]

AI Guidance for Gene Editing

September 12, 2023 | | Posted in Newsletter

AI and CRISPR Precisely Control Gene Expression
“Artificial intelligence (AI) can predict on- and off-target activity of CRISPR tools that target [MORE]

CRISPR in Gene Therapy; Safety Issues

January 3, 2023 | | Posted in Newsletter

Terry Horgan was part of a trial of an experimental gene-editing therapy for muscular dystrophy
“The treatment, which was designated CRD-TMH-001, [MORE]

“SuperFi” Gene Editing

June 14, 2022 | | Posted in Newsletter

SuperFi-Cas9 makes gene editing safer
“A recent study . . . at The University of Texas at Austin (TX, USA) reveals [MORE]

High Efficiency Gene Editing of Human Stem Cells

May 5, 2020 | | Posted in Newsletter

BIG TREE gene editing
To deal with the problem of off target gene editing, researchers at Arizona State University have found [MORE]