POSTS TAGGED AS mRNA

Engineering CRISPR against RNA Viruses

Treatment with Cas13d-NCS prevents the spread of SARS-CoV-2 (green)
“Here, we [at Helmholtz, Munich] show that the nuclear localization of Cas13d [MORE]

Silencing the Bad Cholesterol Gene

Durable and efficient gene silencing in vivo by hit-and-run epigenome editing
“[We, at San Raffaele Telethon Institute for Gene Therapy, Milan, [MORE]

Avian Retrotransposon for Inserting Corrective Genes into the Human Genome

Avian retrotransposon for inserting corrective genes into the human genome.
“Here, we [at UC Berkeley] describe precise RNA-mediated insertion of transgenes [MORE]

Inhalable Exosomes Deliver IL-12 for Treating Lung Cancer

Inhalable exosomes deliver IL-12 lung cancer treatments
“Scientists [at Columbia University] have discovered a way to use inhalable exosomes to deliver [MORE]

Extracellular Vesicles in Diagnosing Gene Expressions in Brains

Blood extracellular vesicles carrying brain-specific mRNAs are potential biomarkers for detecting gene expression changes in the female brain
“We [at Johns [MORE]

Frameshifting with mRNA Therapeutics

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting
“Here we [MRC researchers at the University of Cambridge] demonstrate that incorporation of N1-methylpseudouridine [MORE]

mRNA Loaded Lipid Nanoparticles in Gene Editing

A step toward stem cell engineering in Vivo
“Breda et al. [Children’s Hospital of Philadelphia] designed a strategy to reprogram bone [MORE]

One Shot Gene Therapy for Sickle Cell Disease

One Shot Gene Therapy for Sickle Cell Disease
“On July 27 in Science, scientists from Children’s Hospital of Philadelphia and the [MORE]

Exosomes in Transplanted Organ Rejection

A New Era in Post-Transplant Monitoring
“Of particular relevance to kidney transplant monitoring are the exosomes excreted in urine, which have [MORE]

Lipid Nanoparticles in Treating Preeclampsia

Potential preeclampsia treatment uses LNPs to deliver mRNA to the placenta
“The new study from Swingle and her team [at the [MORE]

mRNA Technology Perspective

Proven mRNA Technologies Embolden Vaccine and Drug Makers
“[mRNA] vaccines progressed from viral sampling to approval more quickly than any other [MORE]

mRNA Nanoparticle that Restores p53 Function in Lab Models

Researchers restore function in Gene (p53) that can suppress liver cancer
“mRNA nanoparticles effectively and safely restored the function of the [MORE]

Ingestible Capsule for mRNA Delivery

Pill that releases mRNA in the stomach to administer vaccines or treat GI disease
“Here, we [engineers at MIT] describe orally [MORE]

Flu-Like Nanoparticles for Gene Transfer

Flu Virus-Inspired Nanoparticles for mRNA Delivery
“Researchers at the University of California San Diego developed a new delivery technique for mRNA. [MORE]