Creating Genetically Humanized Mice
“Historically, genetic humanization of model organisms was achieved through one of two methods: random insertion transgenic humanization [MORE]
History of Creating Genetically Humanized Mice
“Historically, genetic humanization of model organisms was achieved through one of two methods: random insertion [MORE]
Visualizing synaptic plasticity
“We [neuroscientists and engineers at Johns Hopkins] have developed a suite of innovative methodologies that break through these [MORE]
CRISPR
“Knock out” mice—so called because one of several means has been used to inactivate a murine gene—have been invaluable research [MORE]
Since 1929, the Jackson Laboratory on Mt. Desert Island, ME has been breeding strains of mice—now more [MORE]