Making Nanoparticles Stick in the Liver

January 15, 2019 | | Posted in Newsletter

Nanoparticles with hairy polymer shells
Various kinds of nanoparticles are possible drug delivery vehicles in the body.  This report tells of [MORE]

Stem Cells into Functional Liver Tissue

November 6, 2018 | | Posted in Newsletter

Stem cell derived liver cells
Five years ago, researchers reported success in growing liver “buds” (organoids) from stem cells, and three [MORE]

Liver Regeneration

June 12, 2018 | | Posted in Newsletter

An adult’s liver can fully regenerate its original mass from as little as 25% of its remaining undamaged or diseased [MORE]

New Findings for Bioengineering Livers

August 1, 2017 | | Posted in Newsletter

The advantages of culturing tissue in three dimensions have been demonstrated since Alexis Carrel pioneered the hanging drop method in [MORE]

Growing Liver Organoids in a Microfluidic Device

January 31, 2017 | | Posted in Newsletter

Being able to grow liver organoids in a microfluidic device for drug testing in advance of animal or human experiments [MORE]

Organovo’s 3-D Printed Liver Patches for Transplants

November 8, 2016 | | Posted in Newsletter

3-D Printed Liver Tissue
Much of the work in liver tissue regeneration has focused on making micro-organelles for drug testing. But [MORE]

Device to Measure Drug Metabolism in the Liver

September 22, 2015 | | Posted in Newsletter

Liver Drug Analysis
Anticancer drugs are metabolized in the liver before they reach the tumor target—thus a need for a means [MORE]

Order Now: “exVive” 3-D Printed Human Livers

January 20, 2015 | | Posted in Newsletter

Organovo exVive 3D Liver Models
Organovo (San Diego, CA) recently announced that it is now taking orders for 3-D printed human [MORE]

Regenerating Islet Cells

November 11, 2014 | | Posted in Newsletter

This piece is light on the details, but the basic idea is to extract liver cells from a Type 1 [MORE]

Tentative Steps toward Liver Regeneration

October 8, 2013 | | Posted in Newsletter

Shinya Yamanaka
Last year, Japanese scientist Shimya Yamanaka shared the Nobel Prize for Physiology or Medicine for discoveries about converting [MORE]

Growing Livers Outside the Body

August 20, 2013 | | Posted in Newsletter

The liver can regenerate itself naturally, but that has been very difficult to achieve outside the body.  However, researchers [MORE]

First Fully Automated Liver Perfusion Device

April 29, 2013 | | Posted in Newsletter

Liver Organ Device
Until now, liver transplantation was a race against time—i.e. the time a liver “on ice” remained viable, [MORE]

First Engineered Hepatic Vein from Stem Cells Successfully Implanted

September 11, 2012 | | Posted in Newsletter

Taking a nine cm groin vein from a living donor, then stripping it of cells before engrafting a 10 [MORE]

Liver’s Role in Hypertension

March 8, 2011 | | Posted in Newsletter

For over a half century, physiologists have known that blood pressure is controlled by some mechanism outside the brain.  [MORE]