On/Off Switch for CRISPR-Cas9

January 5, 2016 | | Posted in Newsletter

CRISPR Cas9 Mode of Action
CRISPR-Cas9 gene editing has been hailed as the most promising discovery in genomics since PCR. But [MORE]

Proteomic Pathways to Huntington’s Disease

January 5, 2016 | | Posted in Newsletter

The inherited genetic pathology of Huntington’s disease has been known for more than 20 years: in the first exon of [MORE]

Profiling Prostate Cancer

November 24, 2015 | | Posted in Newsletter

Lab Technologist
The PSA assay for prostate cancer is notoriously inaccurate, opening the way for a better diagnostic of this major [MORE]

J. Craig Venter’s $250 Genome for Consumers

November 24, 2015 | | Posted in Newsletter

J. Craig Venter
Entering the race to sequence the human genome after the government-sponsored team had a decade head start with [MORE]

90% of Advanced Prostate Cancers have Clinically Actionable Genetic Aberrations

November 17, 2015 | | Posted in Newsletter

Genetic Counseling
In a collaboration involving eight centers in the US and Europe, researchers sequenced DNA and RNA from tissue biopsies [MORE]

Illumina and You as an App

November 10, 2015 | | Posted in Newsletter

Illumina Gene Sequencing Machines
In what seems like a gigantic opportunity for product liability lawyers, sequencer-maker Illumina plans to launch a [MORE]

A Protein Called “TOPLESS”

October 20, 2015 | | Posted in Newsletter

Why would a biomedical research institute, focusing on cancer, conduct research on plant proteins? The answer explains why the [MORE]

DNA Sequencing at Birth: the BabySeq Project

October 13, 2015 | | Posted in Newsletter

Molecular DNA Model
Since 1970, virtually every baby born in the US has undergone screening with Guthrie tests (a protein analysis [MORE]

Liquid Biopsies for Solid Tumors

October 6, 2015 | | Posted in Newsletter

Blood Test
There are nine companies now in development of liquid biopsies for solid tumors, though none have won FDA approval [MORE]

Genome Sequencing in the Palm of Your Hand

September 8, 2015 | | Posted in Newsletter

Nanopore miniION
It wasn’t that long ago when a DNA sequencer, like the ABI machines the Human Genome Project relied upon, [MORE]

Genetic Link to Autism

August 25, 2015 | | Posted in Newsletter

Protein SHANK3
“Spectrum disorder” actually applies to every disease, but it has gained notable usage in describing autism, where genetic and [MORE]

Mapping DNA Repair in the Human Genome

July 14, 2015 | | Posted in Newsletter

DNA Repair
An unfortunate reality of cancer is that means for killing tumor cells (chemotherapy and radiation) can also cause more [MORE]

Predictive Modeling: the Future of Health Care?

July 7, 2015 | | Posted in Newsletter

Dr. Patrick Soon Shiong
Whether he turns out to be the hero of his own life or that station will be [MORE]

Using CRISPR/Cas for “Knock In” Cassettes

June 30, 2015 | | Posted in Newsletter

“Knock out” mice—so called because one of several means has been used to inactivate a murine gene—have been invaluable research [MORE]