The Genetics Behind Prions

March 22, 2016 | | Posted in Newsletter

This piece is a touching story about young husband and wife researchers at the Broad Institute working on the genetics [MORE]

Proteomic Pathways to Huntington’s Disease

January 5, 2016 | | Posted in Newsletter

The inherited genetic pathology of Huntington’s disease has been known for more than 20 years: in the first exon of [MORE]

Profiling Prostate Cancer

November 24, 2015 | | Posted in Newsletter

Lab Technologist
The PSA assay for prostate cancer is notoriously inaccurate, opening the way for a better diagnostic of this major [MORE]

Understanding p53 in Tumor Cells

November 17, 2015 | | Posted in Newsletter

P53 Pathways
It could be the “holy grail” of cancer science if researchers figured out how to restore p53 tumor suppressor [MORE]

90% of Advanced Prostate Cancers have Clinically Actionable Genetic Aberrations

November 17, 2015 | | Posted in Newsletter

Genetic Counseling
In a collaboration involving eight centers in the US and Europe, researchers sequenced DNA and RNA from tissue biopsies [MORE]

A New and Improved CRISPR

November 3, 2015 | | Posted in Newsletter

Those in the know must be saying “CRISPR-Cas9” is “so yesterday.” This remarkable gene editing technology has shot like [MORE]

New Platform for Cancer Epigenetic Profiling

October 20, 2015 | | Posted in Newsletter

Biostatisticians at Hong Kong Polytechnic University and Harvard University have collaborated to create a new “co-expression” analysis of cancer, on [MORE]

DNA Sequencing at Birth: the BabySeq Project

October 13, 2015 | | Posted in Newsletter

Molecular DNA Model
Since 1970, virtually every baby born in the US has undergone screening with Guthrie tests (a protein analysis [MORE]

A Sensor for “Animal Magnetism”

September 8, 2015 | | Posted in Newsletter

Worm’s Magnetosensor
Before wondering what the roundworm’s burrowing orientation has to do with anything other than C. elegan’s existence, remember that [MORE]

Robotic Drosophila Catcher

August 18, 2015 | | Posted in Newsletter

Drosophila Hangs from Robot’s Suction Tube
This year marks the centennial of a seminal book in the history of genetics: The [MORE]

Perspective on “Next Generation Sequencing”

August 18, 2015 | | Posted in Newsletter

DNA Sequencing
DNA sequencing holds great insight for predicting, diagnosing, preventing, and treating cancer, cardiovascular disease and kidney disease, but the [MORE]

Using CRISPR/Cas for “Knock In” Cassettes

June 30, 2015 | | Posted in Newsletter

“Knock out” mice—so called because one of several means has been used to inactivate a murine gene—have been invaluable research [MORE]

Genetic Map of Great Britain

May 19, 2015 | | Posted in Newsletter

Geneticists at Oxford University and their collaborators have produced the first fine scale genetic map of any country (according to [MORE]

Genetic Observations from DeCode Iceland

May 5, 2015 | | Posted in Newsletter

Decode Genetics
St. Louis, MO has a population of about 320,000, as does Iceland. Based on DNA and genealogy studies of [MORE]