POSTS TAGGED AS Broad Institute

Bacterial System for Protein Delivery

June 27, 2023 | | Posted in Newsletter

Scientists find ‘ultracool’ tiny needle that could someday deliver gene editing therapies
“Gene editing has been limited to a few sites [MORE]

SHERLOCK for RNA Editing

September 27, 2022 | | Posted in Newsletter

CRISPR-Cas13 editing could offer new avenues for treatment
Scientists at the Broad Institute, who were involved in the technology of CRISPR [MORE]

Migraine, Heart Disease, and Hypertension: Three Ailments for the Price of One Gene

September 13, 2022 | | Posted in Newsletter

Broad scientists show how 1 bad gene takes a toll on 5 vascular diseases
Immunologists, among others, know that a single [MORE]

Single Cell Atlas for Defining Disease

July 19, 2022 | | Posted in Newsletter

Single Cell Atlas for Defining Disease
“Here, we [researchers at the Broad Institute and collaborators] applied four single-nucleus RNA sequencing methods [MORE]

Gene Editing for DNA Repair

December 21, 2021 | | Posted in Newsletter

Enhanced prime editing systems
“Toward the goal of enabling a wide range of sequence changes, we [a collaboration of Broad Institute, [MORE]

Another Gene Editing System

November 30, 2021 | | Posted in Newsletter

New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]

Muscle-Tropic Capsids for Gene Transfer

November 30, 2021 | | Posted in Newsletter

Graphical abstract
“Here, we [scientists at the Broad Institute-MIT/Harvard] developed the DELIVER (directed evolution of AAV capsids leveraging in vivo expression [MORE]

SEND (Selective Endogenous eNcapsidation for Cellular Delivery)

November 9, 2021 | | Posted in Newsletter

mRNA gene therapy with a human protein
For a generation, gene therapy has relied on viral vectors to deliver a transgene.  [MORE]

World’s Largest Browsable Resource Linking Rare Protein-Coding Genetic Variants to Human Health and Disease

October 12, 2021 | | Posted in Newsletter

Genebass resource linking protein-coding variants to health and disease
“Genebass [sic] is a resource of exome-based association statistics, made available to [MORE]

A COVID-19 Biobank

July 7, 2020 | | Posted in Newsletter

Last February, when more than 100 Biogen representatives from around the world attended a conference, they unwittingly became a means [MORE]

Repurposing Drugs against Cancer

April 14, 2020 | | Posted in Newsletter

Repurposed medications
MAIN does not ordinarily carry drug-related news, but in this case, repurposing existing drugs to previously unknown targets really [MORE]

A Neonate Genetic Screen for Lifelong Obesity Risk

September 10, 2019 | | Posted in Newsletter

Polygenic score to predict obesity risk
Researchers at the Broad Institute have developed a polygenic test that could be given to [MORE]

Multigene Test for High Risk Heart Disease, et al

December 18, 2018 | | Posted in Newsletter

DNA Multigenic risk score
Polygenic risk scores may become as routine as cholesterol screening. To that end, researchers at the Broad [MORE]

Cell Atlas of the Small Intestine

December 12, 2017 | | Posted in Newsletter

Small Intestine Cellular Composition
Quoting directly: “The lining or epithelium of the gut is one of the body’s most diverse and [MORE]