Scientists find ‘ultracool’ tiny needle that could someday deliver gene editing therapies
“Gene editing has been limited to a few sites [MORE]
CRISPR-Cas13 editing could offer new avenues for treatment
Scientists at the Broad Institute, who were involved in the technology of CRISPR [MORE]
Broad scientists show how 1 bad gene takes a toll on 5 vascular diseases
Immunologists, among others, know that a single [MORE]
Single Cell Atlas for Defining Disease
“Here, we [researchers at the Broad Institute and collaborators] applied four single-nucleus RNA sequencing methods [MORE]
Enhanced prime editing systems
“Toward the goal of enabling a wide range of sequence changes, we [a collaboration of Broad Institute, [MORE]
New Gene Editing Proteins Found Outside of CRISPR Systems
“Scientists at MIT’s McGovern Institute and the Broad Institute of MIT and [MORE]
Graphical abstract
“Here, we [scientists at the Broad Institute-MIT/Harvard] developed the DELIVER (directed evolution of AAV capsids leveraging in vivo expression [MORE]
mRNA gene therapy with a human protein
For a generation, gene therapy has relied on viral vectors to deliver a transgene. [MORE]
Genebass resource linking protein-coding variants to health and disease
“Genebass [sic] is a resource of exome-based association statistics, made available to [MORE]
COVID-19
Last February, when more than 100 Biogen representatives from around the world attended a conference, they unwittingly became a means [MORE]
Repurposed medications
MAIN does not ordinarily carry drug-related news, but in this case, repurposing existing drugs to previously unknown targets really [MORE]
Polygenic score to predict obesity risk
Researchers at the Broad Institute have developed a polygenic test that could be given to [MORE]
DNA Multigenic risk score
Polygenic risk scores may become as routine as cholesterol screening. To that end, researchers at the Broad [MORE]
Small Intestine Cellular Composition
Quoting directly: “The lining or epithelium of the gut is one of the body’s most diverse and [MORE]